DR.MESO® Triple Action Retinol Night Serum for mature skin
DR.MESO® Retinol Night Serum for dry and mature skin
DR.MESO Triple Action Retinol Night Serum for mature and sensitive-feeling skin
DR.MESO Retinol Night Serum for smoother, radiant-looking mature skin
DR.MESO Collagène skincare with Retinol Night Serum for dry mature skin
DR.MESO Collagène routine for dry, mature and sensitive-feeling skin
DR.MESO® Triple Action Retinol Night Serum for mature skin
DR.MESO® Retinol Night Serum for dry and mature skin
DR.MESO Triple Action Retinol Night Serum for mature and sensitive-feeling skin
DR.MESO Retinol Night Serum for smoother, radiant-looking mature skin
DR.MESO Collagène skincare with Retinol Night Serum for dry mature skin
DR.MESO Collagène routine for dry, mature and sensitive-feeling skin

Triple Action Retinol Night Serum for Mature Skin | DR.MESO®

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$110.00 CAD

Why This Retinol + Retinal Night Serum Is Different

DR.MESO® Triple Action Retinol Night Serum is an evening renewal serum for dry, mature and sensitive-feeling skin. It combines Retinol and Retinaldehyde with Niacinamide, Hyaluronic Acid, Vitamin E and Glycerin to support smoother-looking texture, hydration and skin comfort while helping improve the appearance of fine lines and dullness.

Key Benefits

  • Helps smooth the look of uneven skin texture
  • Helps reduce the appearance of fine lines
  • Supports a brighter, more refined-looking complexion
  • Niacinamide, Hyaluronic Acid and Glycerin support hydration and comfort
  • Vitamin E provides antioxidant skin-conditioning support
  • Made in Canada

Retinol vs Retinal — What’s the Difference?

Retinol and Retinaldehyde (Retinal) are both forms of Vitamin A used in nighttime skincare. DR.MESO® combines both in one targeted formula to support gradual skin renewal and a smoother, more refined-looking complexion.

Retinol — supports gradual evening skin renewal and helps improve the look of uneven texture and visible signs of aging.

Retinaldehyde (Retinal) — another Vitamin A form that supports skin renewal and smoother-looking texture.

Hydration + Comfort Support

Niacinamide supports the skin barrier and helps improve the look of uneven tone.

Hyaluronic Acid and Glycerin help support hydration and moisture retention.

Vitamin E (Tocopherol) provides antioxidant and skin-conditioning support.

Best For

Dry, mature, dull-looking or sensitive-feeling skin with concerns about fine lines, uneven texture and loss of radiance.

How to Use

Use in the evening after cleansing and toner. Start 2–3 nights per week and increase gradually according to skin tolerance. Avoid the eye area. Use broad-spectrum SPF during the day.

Caution: Do not use during pregnancy or nursing.

Learn More: Retinol vs Retinal

Want to understand why this formula combines both Vitamin A forms? Read our guide: Retinol vs Retinal: What’s the Difference for Mature & Sensitive Skin?

Read more

COMPLETE YOUR SKIN ROUTINE
Woman rinsing face after using Dr. Meso cleanser
Step 1

Wash face with Collagene Cleansisng Lotion

Woman applying Dr. Meso peel with sponge
Step 2

Apply Collagene Toner with cotton swab or sponge

Woman applying Dr. Meso Eye serum
Step 3

Apply Collagene Triple Action Retinol Serum at night time before bed

Woman's face with Dr Meso cream dabbed on cheek
Step 4

For best results, apply Collagene Night Gel at night time before bed on top of Retinol Serum
Customers rate us 5.0/5 based on 74 reviews.

Let customers speak for us

from 74 reviews

As a man, I really liked their hair products and face cream from the collagen line. The cream has nice texture and good moisturising
With shampoo my hair was fresh longer.

RedDragon Emil

I started using their hair care line for PCOS-related hair loss on my ND’s recommendation. Their shampoo, conditioner and hair mask really helped to reduce hair fall in the shower. I didn’t notice as much new growth though. I had to combine other methods with their products to see new hair growth (minoxidil, dermarolling, and rosemary water to name a few). Overall, very happy with how clean and effective their products are!

Tharshni Velauthapillai

I'm in love with the whole line... The peel is absolutely fantastic... I work at a hair school and medical aesthetic school
I love this product so much I'm hoping to carry it with our school

Kimberly M

I purchased the face mask, oily-free line for my family. The entire system works well(We've used the entire line before). I'm trying their other skincare products, I'll let you know the progress.

There SheGrows

I am so happy that Dr. Meso exists! I am a Transcendental Intuitive Healer and former aesthetician and was looking for Europian wisdom purity in self-care products that would be Canadian, Organic, Homeopathic with supplements and prices that are moderate for the quality it brings. Easy protocols and deep penetration of fine formular - I just LOVE it! Well thought!

Sonja

Great products! Great service! I've been a customer for a long time. Very happy about the results.

Ludmyla Koel

Been using Mr. Meso products for over two years now. Love the fact that they are made in Canada. After regular use, my skin is glowing and completely acne free. As of today, my favorite go to are detox mask and collagen night cream.

Maria Rastoropina

Last week I went for a skin treatment and was recommended the Liftox Cream by Dr. Mezo. I was impressed by the effect of this cream. It provides supreme toning, lifting, and moisture to my dull saggy skin. In addition, it comes in a box with a pleasant soft touch. I could not believe that it was made of recycled paper. It was very easy to take the jar out of this nice double wall box. The jar itself is so beautiful, like a jewel. It has a pump which makes it very convenient to get the cream without sticking my fingers into the jar. I would highly recommend this product if you like to get a good cosmetic effect and aesthetic pleasure.

Natalia “Natalka M” M

The Dr. Meso acne free cleanser and toner have helped clear my acne and control my oily skin without drying it out! The cleanser is very gentle, yet effective and the toner is very refreshing! Liliana was very helpful in suggesting products and offering knowledgable advice. Can't wait to try other products in the acne free line!

Kylie Johnston

Best quality products and prices are great!! I'm all acne-free now!

Danylo Dutka